BigWig Manipulation

bigWigMerge
Function: Merge together multiple bigWigs into a single output bedGraph.
Usage: bigWigMerge [options] in1.bw in2.bw .. inN.bw out.bedGraph
Supported input format: bigWig
bigWigAverageOverBed
Function: Averaging scores in a bigWig file for the regions/intervals given in a bed file
Usage: bigWigAverageOverBed [options] in.bw in.bed out.tab
Supported input format: BED, bigWig
wigCorrelate
Function: Produce a table that correlates all pairs of wig or bigWig files
Usage: wigCorrelate [options] one.wig two.wig ... n.wig
Supported input format: bigWig, WIG
bigWigCorrelate
Function: Correlate bigWig files, optionally only on target regions.
Usage: bigWigCorrelate [options] a.bigWig b.bigWig
Supported input format: bigWig
bigWigSummary
Function: Extract binned summary information from a bigWig file for a genomic region
Usage: bigWigSummary [options] file.bigWig chrom start end dataPoints
Supported input format: bigWig
bigWigInfo
Function: Print out summary information about bigWig file. The summary statistics include mean, min, max, std, and bases covered.
Usage: bigWigInfo [options] file.bw
Supported input format: bigWig
multiBigwigSummary
Function: Compute the average scores for each of the bigWig files in every genomic region.
Usage: multiBigwigSummary bins -b file1.bw file2.bw -out results.npz [options]
Supported input format: bigWig
wiggletools sum
Function: Merge bigWig files
Usage: wiggletools sum [bigwig files...]
Supported input format: bigWig,WIG
bigWigCat
Function: Merge non-overlapping bigWig files directly into bigWig format
Usage: bigWigCat [options] out.bw in1.bw in2.bw ...
Supported input format: bigWig